In an acute attack of angina, any precipitating factor - exercise in exertional angina, or lying down in decubitus angina should be stopped, and a fresh glyceryl trinitrate tablet (0.5 mg) should be placed under the tongue. Pain usually recedes within 3 minutes.
When the pain is relieved the trinitrate tablet is spat out or swallowed, in order to minimise the risk of developing side effects, in particular a severe pounding headache.
Frequent or prolonged angina attacks need urgent review and consideration for urgent hospital admission because of possible unstable angina or myocardial infarction.
NICE state with respect to using short-acting nitrate in angina
Reference:
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