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Factors associated with a higher risk of recurrence

Authoring team

There are several factors that may have an effect on recurrence rate including histological sub-type, other histological features, site, and other patient and tumour features.

Histological sub-type

  • morphoeic – linear groups of cancer cells with surrounding scarring; clinically this causes a thickened and hardened skin
  • infiltrating – like morphoeic but with less scarring
  • micronodular – very small groups of cancer cell
  • basosquamous carcinoma – a skin cancer with both basal and squamous elements

Histological features

  • perineural invasion
  • invasion below dermis

Sites

  • nose and paranasal folds
  • periocular
  • ears
  • scalp and temples
  • lips

Other factors

  • size > 2 cm
  • immunosuppression
  • genetic disorders such as Gorlin’s syndrome
  • previously treated lesion

Reference:

  1. NICE (February 2006).CSG Improving Outcomes for People with Skin Tumours including Melanoma: The Manual

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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