This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Carbimazole / propylthioruacil in thyrotoxicosis

Authoring team

Either carbimazole or propylthiouracil are prescribed in high doses initially - carbimazole 15 to 40 mg per day; propylthiouracil 200-400 mg per day. This single dose promotes compliance. Treatment may then either follow a gradual dose titration regime, or a block and replace regime. 'Long-term remission rates with two regimens are similar.'

Symptomatic improvement is often detected within 3-4 weeks and normal T3 and T4 values are achievable within 2-3 months.

Treatment is usually continued for 18 months. Over 50% relapse within 2 years with a small continuing relapse rate thereafter. Most relapses occur within 4 years.


Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.