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Glucose metabolism

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Glucose metabolism centres around the maintenance of blood glucose levels within a standard range and the co-ordination of fuel utilization with other reserves e.g. lipids and ketone bodies.

Essentially, blood glucose levels are dependent on the balance between output - breakdown for energy - and input - dietary absorption and release either from storage or by interconversion from other compounds.

Glucose storage predominantly occurs in the liver as glycogen. The biochemical pathways of the liver are adapted to release glucose in response to reductions in the plasma glucose concentration and modulation by various hormones. Pathways include glycogenolysis and gluconeogenesis.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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