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Prevalence

Authoring team

KS is the commonest chromosomal abnormality seen in men with 0.1–0.2% of the males being affected (1)

  • according to six large surveys of consecutive newborns carried out in 1960s and early 70s the prevalence of KS was 1 per 1000 same sex births while a higher prevalence (up to 1 in 500 boys) was observed in studies carried out later
  • findings suggest that the prevalence of KS has increased in opposition to the other sex chromosome trisomies (47,XYY males and 47,XXX females) (1)

A large Danish study revealed that only 25% of patients were identified postnatally out of which less than 10% were diagnosed before puberty (2).

  • these numbers are similar to those from UK where only 26% of the expected adults with KS have been identified


Reference:

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