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Normal or raised TSH, raised free thyroid hormones

Authoring team

Normal or elevated TSH in the presence of raised free thyroid hormones is a rare disorder but may be clinically important.

The causes of this pattern of abnormality are:

  • artefact - need to repeat the tests
  • interfering antibodies
  • familial dysalbuminaemic hyperthyroxinaemia
  • amiodarone therapy
  • thyroid hormone receptor mutations
  • acute psychiatric disease
  • TSH secreting pituitary tumour
  • intermittent thyroxine overdosage

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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