Lynch syndrome is a genetic condition caused by germ line mutations or alterations in any one of the four genes known as mismatch repair (MMR) genes
Lynch syndrome is transmitted in a mendelian autosomal-dominant (AD) pattern of inheritance whereby individuals with Lynch syndrome have a 50% chance of transmitting the genetic mutation to each of their offspring. Individuals with Lynch syndrome are born with a normal functioning gene (wild type allele) on one chromosome and a mutated gene on the other chromosome
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