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Diagnosis and treatment

Authoring team

Diagnosis is by specific inhibitor activity.

Treatment depends upon the inhibitor level.

Approaches include:

  • immunosuppression to reduce antibody production
  • plasmaphoresis to reduce inhibitor levels
  • massive infusion of the appropriate factor
  • infusion of Factor IX concentrates for Factor VIII inhibitor - may bypass the inhibited clotting factor
  • Factor VIIa with Factor VIII bypassing activity
  • cyclophosphamide, usually combined with prednisolone, or porcine Factor VIII, may be used in Factor VIII inhibition

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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