Pyruvate carboxylase is a mitochondrial enzyme that converts pyruvate, bicarbonate ions and ATP into oxaloacetate, ADP and phosphate. It is used in gluconeogenesis as a stage in the interconversion of pyruvate to phosphoenolpyruvate. Also, it may provide oxaloacetate precursors for the tricarboxylic acid cycle at times of exercise.
It is inhibited by an increased concentration of intracellular ADP.
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page