swelling and redness at the injection site and low grade fever are among the most commonly reported adverse reactions (10–20%)
no increased local or systemic reactions have been reported with repeated doses during the primary series, although a higher rate of transient tenderness has been reported after a fourth dose
pneumococcal polysaccharide vaccine (PPV)
mild soreness and induration at the site of injection lasting one to three days
lless commonly, a low grade fever may occur
more severe systemic reactions are infrequent. In general, local and systemic reactions are more common in people with higher concentrations of antibodies to pneumococcal polysaccharides
confirmed anaphylaxis involving pneumococcal vaccines is rare. Other allergic conditions, such as rashes, may occur more commonly and are not contraindications to further immunisation (1)
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