disinhibition of detrusor muscle - produces a combination of urgency and incontinence. The severe physical disabilities may prevent patient from reaching the lavatory in time.
complete urinary retention is often an early feature
retention associated with urinary tract infection - the resulting cystitis exacerbates the urgency and incontinence, and so a vicious cycle occurs
impotence
Uhthoff's phenomenon
epilepsy
facial myokymia
in advanced disease - euphoria or depression, social disinhibition, impaired memory, frank dementia
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