Tiagabine

Home

Pages

Neurology

Add annotation to this page

Authoring team

Tiagabine has been licensed as an add-on agent in the treatment of partial seizures, with or without secondary generalisation not satisfactorily controlled with other antiepileptic medication.

Tiagabine has a short elimination half-life (5-9 hours) which can be shortened further (2-4 hours) in patients taking enzyme-inducing drugs such as carbamazepine (1).

Tiagabine works by inhibiting the reuptake of GABA into neurones and glia.

has also been used to treat anxiety disorders and neuropathic pain (including fibromyalgia)

for anxiety and neuropathic pain, tiagabine is used primarily to augment other treatments

tiagabine may be used alongside SSRIs, SNRIs or benzodiazepines for anxiety, or antidepressants, gabapentin, anticonvulsants or opiates for neuropathic pain (2)

The summary of product characteristics should be consulted before prescribing this drug.

Drug and Therapeutics Bulletin (2000), 38 (6), 47-48.

Stahl, S. Stahl's Essential Psychopharmacology: Prescriber's Guide. Cambridge University Press: New York, NY. 2009. pp. 523-526

Annotations let you add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. Reflective notes let you add information to the CPD dashboard based on the content of this page: what did you learn from it and how might it change your practice?

Annotations let you add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

Tiagabine

Related pages

Create an account to add page annotations