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gastrointestinal antispasmodics during breastfeeding

Authoring team

A review states (1):

  • hyoscine butylbromide, propantheline or peppermint oil are considered preferred choices in breastfeeding
    • mebeverine and alverine can also be used
  • is limited evidence for the use of antispasmodics during breastfeeding and therefore recommendations are generally made on the properties of the medicine
    • choice of medicine will depend on symptoms
    • is a theoretical risk that suppression of breast milk production could occur with antimuscarinic drugs (atropine, hyoscine butylbromide, propantheline)
    • have been conflicting reports that peppermint may increase or decrease breast milk production
      • is no published evidence to support this
  • once breastfeeding is established, any effect on breast milk production becomes less significant
  • advisable to monitor breastfed infants for adequate feeding and poor weight gain, especially if used long-term

Reference:


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